Principal Generative AI Engineer

Conshohocken, PA
Full Time
Information Technology
Experienced
As a Generative AI Engineer at Madrigal Pharmaceuticals, you will be at the forefront of integrating advanced AI technologies to drive innovation within the pharmaceutical industry. You will create business-facing experiences that highlight the value LLMs can bring to our organization and lead the development and implementation of our Generative AI roadmap.

Position Responsibilities: 
  • Technical Leadership and Strategy:
    • Develop and manage the Generative AI roadmap.
    • Identify critical business problems that can be solved using Generative AI.
    • Define and implement strategies for leveraging Generative AI within the organization.
    • Lead discussions in peer reviews and use quantitative skills to influence decision-making positively.
  • Solution Architecture and Design:
    • Ensure the appropriate level of LLM complexity for various use cases (e.g., Dolly vs. GPT-4).
    • Create technical standards and blueprints for Generative AI scenarios.
    • Lead prompt engineering efforts to optimize LLM performance.
    • Quickly prototype and test LLM scenarios to refine user experiences.
  • Advanced Analytics, Data Science, and Machine Learning:
    • Strong theoretical background and extensive experience in machine/deep learning, generative AI, and statistical modeling.
    • Spearhead fine-tuning of LLMs and building RAG (Retrieval-Augmented Generation) systems.
    • Develop and embed automated processes for predictive model validation, deployment, and implementation.
    • Influence the AI/ML stack, including Feature Stores, Model Stores, and automated MLOps, to maximize the value of LLMs.
    • Make impactful contributions to internal discussions on emerging machine learning methodologies.
  • Cross-Functional Collaboration:
    • Work with cross-functional teams, including data scientists, data engineers, and research scientists, to deliver features iteratively.
    • Lead internal and external developers to execute the Generative AI roadmap.
    • Connect and collaborate with subject matter experts across different business areas.
    • Educate technical and business leaders on the use of Generative AI.
  • Continuous Learning and Innovation:
    • Demonstrate a combination of business focus, strong analytical and problem-solving skills, and programming knowledge to quickly cycle hypotheses through the discovery phase of projects.
    • Report findings clearly and structurally through excellent written and communication skills.
    • Stay updated with the latest advancements in Large Language Models (LLMs) and apply them to business scenarios.
Qualifications and Skills Required:
  • Advanced degree (Ph.D. preferred) in Engineering, Statistics, Data Science, Applied Mathematics, Computer Science, Physics, Bioinformatics, or a related quantitative field.
  • 10+ years of proficiency in Python, SQL, R, MATLAB, PyTorch, Keras, and git.
  • 8+ years of experience in ML/deep learning, including hands-on experience with LLM fine-tuning and/or training (e.g., ChatGPT, BERT, Bard, LLaMA, Dolly).
  • 8+ years of experience in data visualization and creating dashboards/web applications using Python and R-based tools (Dash, Streamlit, Shiny).
  • 8+ years of experience in data manipulation, integration, writing complex queries, and creating data products.
  • 8+ years of implementing AI/ML systems using platforms like Databricks or Dataiku.
  • Strong understanding of cloud-based data platforms and technologies (e.g., AWS, Azure, Google Cloud) and their application in building scalable and efficient analytics solutions.
  • Proven experience in machine learning and software engineering best practices.
  • Demonstrated ability in writing and presenting papers, documentation, and presentations to explain research findings.
  • Fluency in English.
Compensation:
Base salary is determined by several factors that include, but are not limited to, a successful candidate's qualifications, skills, education, experience, business needs, and market demands. The role may also be eligible for bonus, equity, and comprehensive benefits, which include flexible paid time off (PTO), medical, dental, vision, and life and disability insurance.

#LI-Hybrid

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Please be aware that we are currently receiving numerous reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Interviews with Madrigal are conducted via the Zoom platform.

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks.

Share

Apply for this position

Required*
We've received your resume. Click here to update it.
Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or Paste resume

Paste your resume here or Attach resume file

To comply with government Equal Employment Opportunity and/or Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated. Learn more.

Invitation for Job Applicants to Self-Identify as a U.S. Veteran
  • A “disabled veteran” is one of the following:
    • a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or
    • a person who was discharged or released from active duty because of a service-connected disability.
  • A “recently separated veteran” means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
  • An “active duty wartime or campaign badge veteran” means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
  • An “Armed forces service medal veteran” means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Veteran status



Voluntary Self-Identification of Disability
Voluntary Self-Identification of Disability Form CC-305
OMB Control Number 1250-0005
Expires 04/30/2026
Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Please check one of the boxes below:

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

You must enter your name and date
Human Check*